A genetic mutation affecting microglia, the brain's immune cells, can increase the risk of Alzheimer's disease up to threefold. The mutation, known as TREM2 R47H/+, impairs microglia function and contributes to Alzheimer's pathology.
A genetic mutation affecting microglia, the brain's immune cells, can increase the risk of Alzheimer's disease up to threefold. The mutation, known as TREM2 R47H/+, impairs microglia function and contributes to Alzheimer's pathology.